Christopher Breen Eli Lilly and Company Thu, 11/10/2016 - 3:30pm Room 306, Statistics Building 1130 Monitoring the control and capability of process parameters is a continual and mammoth task for today’s manufacturers. The importance of simple, efficient, and automated approaches cannot be overstated. Paramount in this endeavor is the determination of extreme quantiles. I will review approaches for determining these quantile from the last 25 years of literature, as well as current usage at Eli Lilly and Company. A number of candidate approaches will be carried forward into a simulation to look at their performance against a variety of distributions. http://www.ispe.org/index.php/ci_id/2888/la_id/1/s_id/359814.htm