Skip to main content
Skip to main menu Skip to spotlight region Skip to secondary region Skip to UGA region Skip to Tertiary region Skip to Quaternary region Skip to unit footer

Slideshow

Jaejik Kim

Kim
<a href=http://www.biostat.mcg.edu/Faculty&Staff/JKim.html>Medical College of Georgia</a>

Salivary glands are important for producing salivary proteins which contribute to host defense, lubrication, and digestion. However, salivary glands are often damaged or destroyed by radiation therapy or surgery for head and neck cancers, or by advanced Sjogrens syndrome. In order to engineer or replace salivary glands, it is important to define the major intracellular pathways of the nuclear program that causes terminal differentiation of the parotid acinar cells. Gene network discovery is a critical part to do this. Under this situation, Li (2010) proposed an ordinary differential equation (ODE) model for three genes which have important roles in recovering salivary gland cells. However, in practice, the functional relationships between these three genes are unknown and Li's model does not follow the law of mass-action. Thus, we compare Li's model with a model following the law of mass-action and investigate their validity for observed mRNA expression time series data using the Bayesian approach.

Support us

We appreciate your financial support. Your gift is important to us and helps support critical opportunities for students and faculty alike, including lectures, travel support, and any number of educational events that augment the classroom experience. Click here to learn more about giving.

Every dollar givenĀ has a direct impact upon ourĀ students and faculty.